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Image: Patrice O'Neal
Dan Krauss  /  AP file
Patrice O'Neal is seen at the Comedy Central "Roast of Charlie Sheen" on Saturday, Sept. 10, in Culver City, Calif.
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updated 11/29/2011 2:04:07 PM ET 2011-11-29T19:04:07

Patrice O'Neal, RIP.

The outsized funnyman who kept America laughing via a series of cable specials and capped in August by an uproarious appearance on Comedy Central's "Roast of Charlie Sheen" has died from complications due to a stroke suffered last month.

He was 41.

MORE: Charlie Sheen Tweets Get Well to Pal Patrice O'Neal

"Yes it's true that our pal Patrice O'Neal has passed away. The funniest and best thinker i've ever known PERIOD," tweeted Opie from Sirius XM Radio's "Opie and Anthony Show," where O'Neal frequently guested.

The shockjock also linked to a YouTube video of O'Neal joking around in the studio.

On Oct. 19, Opie and Anthony broke the news via Facebook that O'Neal endured a stroke and urged listeners to keep him in their prayers as it was unclear whether he'd recover.

Besides being a regular guest of the radio cut-ups, O'Neal was best known for a string of half-hour HBO and Showtime stand-up specials following his breakthrough on HBO's "Def Comedy Jam" in 2007. His first hourlong special, "Elephant in the Room," debuted on Comedy Central last February.

The comedian was also a regular on Comedy Central's "Tough Crowd With Colin Quinn" for two years and performed on "The Late Show With David Letterman" and "Late Night With Conan O'Brien."

He also had guest shots on "The Office," "Arrested Development," and "Chappelle's Show" among others.

No word yet on funeral plans.

GALLERY: Celebrity deaths of 2011

© 2012 E! Entertainment Television, Inc. All Rights Reserved.

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